Related Experiment Video
Updated: Dec 24, 2025
07:44
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
6.4K
EUS-guided biliary drainage: A systematic review and meta-analysis.
Banreet Singh Dhindsa1, Harmeet Singh Mashiana2, Amaninder Dhaliwal2
1Department of Internal Medicine, University of Nevada Las Vegas School of Medicine, Las Vegas, Nevada, USA.
Endoscopic Ultrasound
|April 17, 2020
Summary
Endoscopic retrograde cholangiopancreatography (ERCP) is standard for biliary obstruction. Endoscopic ultrasound-guided biliary drainage (EUS-BD) offers high success rates and is an effective alternative, though adverse events require careful consideration.
Area of Science:
- Gastroenterology and Hepatology
- Interventional Endoscopy
- Biliary Interventions
Background:
- Endoscopic retrograde cholangiopancreatography (ERCP) is the primary treatment for jaundice due to biliary obstruction.
- Endoscopic ultrasound-guided biliary drainage (EUS-BD) has emerged as a viable alternative for patients needing biliary drainage.
Purpose of the Study:
- To systematically review and meta-analyze the efficacy and safety of EUS-guided biliary drainage (EUS-BD).
- To report the overall technical success, clinical success, and adverse event rates associated with EUS-BD.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, EMBASE, Web of Science, Google Scholar, LILACS) up to June 2018.
- Included studies reported on EUS-BD in patients with biliary obstruction.
- Primary outcomes were technical and clinical success; secondary outcomes included re-intervention and adverse event rates.
Main Results:
- Twenty-three studies comprising 1437 patients and 1444 procedures were analyzed.
- Pooled technical success rate was 91.5% and clinical success rate was 87%.
- Overall adverse event rate was 17.9%, with specific rates for bile leak (4.1%), stent migration (3.9%), and infection (3.8%).
Conclusions:
- EUS-guided biliary drainage (EUS-BD) demonstrates high technical and clinical success rates, establishing it as an effective procedure.
- While effective, careful consideration of potential adverse events and comparison with alternative treatments is necessary.
- Publication bias is a potential concern that warrants attention in future research.
