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A Rare Case of a Distal Humerus Pathological Fracture from Klebsiella Pneumoniae Osteomyelitis: A Case Report
Abstract:
Klebsiella pneumoniae is one of the leading causative organisms in pyogenic liver disease. It can cause disseminated infections, but rarely to bone, and rarely in healthy hosts. We report an unusual case of a distal humerus fracture from osteomyelitis secondary to dissemination in a non-immuno-compromised patient. The patient was surgically managed with external fixation and insertion of anti-biotic beads, in conjunction with medical therapy via culture direct antibiotics. This report highlights the diagnostic approach and treatment options for these atypical cases.
Insights
Klebsiella pneumoniae rarely causes bone infections in healthy individuals. This case details a humerus fracture due to osteomyelitis from Klebsiella pneumoniae dissemination, highlighting diagnosis and treatment for such rare occurrences.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Bacteriology
Background:
- Klebsiella pneumoniae is a significant cause of pyogenic liver disease.
- Disseminated Klebsiella pneumoniae infections are uncommon, especially in healthy hosts and bone.
- Osteomyelitis is a serious bone infection that can result from bacterial spread.
Observation:
- A non-immuno-compromised patient presented with a distal humerus fracture.
- The fracture was secondary to osteomyelitis caused by Klebsiella pneumoniae.
- The infection disseminated from an unknown primary source.
Findings:
- Surgical management included external fixation and antibiotic beads.
- Medical therapy involved culture-directed antibiotics.
- The patient's humerus fracture was successfully treated.
Implications:
- This case underscores the importance of considering disseminated Klebsiella pneumoniae in atypical presentations.
- It highlights effective diagnostic and therapeutic strategies for rare osteomyelitis cases.
- Further research into Klebsiella pneumoniae dissemination in healthy hosts may be warranted.

