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Updated: Dec 24, 2025

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
[Traumatic brain injury in drug users]
1Department of Pathological Anatomy and Forensic Medicine of the Ural State Medical University, Ekaterinburg, Russia.
Abstract:
We assessed the incidence of mechanical injury in drug users. Incidence was 21.9% and exceeds the global average injury rate by 2.4 times Mortality from mechanical injury among drug users ranges from 4.46% to 5%. This value is 4.46-5%, which is 64-71 times higher than the average mortality rates from injury and 89-100 times higher than trauma mortality rate in Russia. Psychoactive drugs from the groups of neurostimulators and neurodepressors have a significant impact on the course of traumatic brain injury; hallucinogens only increase the risk of traumatic injury. In cases of mild traumatic brain injury and concussion combined with drug intoxication, the action of the psychoactive drug is the leading link of pathogenesis. In cases of moderate to severe traumatic brain injury combined with drug intoxication, craniocerebral trauma determines the outcome.
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