Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chirality02:25

Chirality

28.8K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
28.8K
Chirality in Nature02:30

Chirality in Nature

16.3K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
16.3K
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

14.6K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
14.6K
Prochirality02:05

Prochirality

4.7K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
4.7K
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

6.7K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
6.7K
Properties of Enantiomers and Optical Activity02:24

Properties of Enantiomers and Optical Activity

20.8K
It is essential to understand the difference between chiral and achiral interactions and the implications thereof in optical activity and their applications. Just as our feet, which are chiral, interact uniquely with chiral objects, such as a pair of shoes, but identically with achiral socks, enantiomers of a molecule exhibit different properties only when they interact with other chiral media. An example of a significant implication from this facet is the phenomenon known as optical activity,...
20.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chiral-Induced Spin Selectivity Effect in a 1 nm Thin 1,1'-Binaphthyl-2,2'-diyl Hydrogenphosphate Self-Assembled Monolayer on Nickel Oxide.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Enantiospecific Magnetoconductance Asymmetry in a Racemic Conglomerate Driven by Surface-Assisted Symmetry Breaking.

Journal of the American Chemical Society·2026
Same author

Close-Shell and Biradical Enantiomers for Probing the Chiral-Induced Spin Selectivity Effect.

The journal of physical chemistry letters·2026
Same author

Dynamic breaking of mirror symmetry in spin-dependent electron transport through chiral media causes enantiomeric excesses.

Science advances·2026
Same author

Temperature-Enhanced Coercive Field by Chiral Molecules.

The journal of physical chemistry letters·2026
Same author

Emergence of magnetic monopole-like behavior in iron oxide nanoparticles grafted with chiral brushes: a chiral induced spin selectivity manifestation.

Materials horizons·2026
Same journal

Solid-State NMR Quantification of Brønsted-Lewis Acid Site Cooperativity in Zeolites for Glucose Conversion.

The journal of physical chemistry letters·2026
Same journal

Ion-Pairing-Mediated Selective Transport of Rare Earth Elements through Functionalized Graphene Nanopores.

The journal of physical chemistry letters·2026
Same journal

Ligand-Tuned CISS-Effect of Atomically Precise Metal Oxido Nanoclusters.

The journal of physical chemistry letters·2026
Same journal

Data-Driven Exploration of the Polyethylene Catalyst Chemical Space via Machine Learning.

The journal of physical chemistry letters·2026
Same journal

Role of Ultrafast Electron-Thermal-Phonon Interactions in High Harmonic Generation and Dephasing from Graphene.

The journal of physical chemistry letters·2026
Same journal

Real-Time Vibrational Spectroscopy Reveals an Inversion Transition State in the Photoisomerization of Phenylazoimidazole.

The journal of physical chemistry letters·2026
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.8K

Chiral Molecules and the Spin Selectivity Effect.

R Naaman1, Y Paltiel2, D H Waldeck3

  • 1Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel.

The Journal of Physical Chemistry Letters
|April 17, 2020
PubMed
Summary
This summary is machine-generated.

Recent experiments reveal the chiral induced spin selectivity (CISS) mechanism in chiral molecules. This mechanism enhances spin polarization via spin blockade, leading to significant spin filtering effects in electronic and magnetic properties.

More Related Videos

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.6K
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

11.0K

Related Experiment Videos

Last Updated: Dec 24, 2025

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.8K
A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.6K
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

11.0K

Area of Science:

  • Condensed Matter Physics
  • Materials Science
  • Organic Chemistry

Background:

  • Chiral molecules exhibit unique electronic and magnetic properties.
  • The chiral induced spin selectivity (CISS) mechanism is a key phenomenon.
  • Understanding CISS is crucial for developing novel spintronic devices.

Purpose of the Study:

  • To review recent experimental findings on the CISS mechanism.
  • To explore the manifestation of CISS in chiral molecules and materials.
  • To elucidate the underlying physical principles governing CISS.

Main Methods:

  • Discussion of recent experimental studies on CISS.
  • Analysis of magnetization dependence in chiral molecule-ferromagnetic surface interactions.
  • Review of early experiments on spin filtering and applied potential.

Main Results:

  • Experiments highlight the role of exchange interactions and Pauli exclusion in CISS.
  • Demonstration of spin-dependent charge flow between ferromagnetic substrates and chiral molecules.
  • Theoretical models often require large spin-orbit couplings to explain experimental observations.

Conclusions:

  • CISS involves spin-dependent charge flow and is influenced by exchange interactions.
  • A simplified model incorporating spin blockade enhances chiral molecule spin polarization.
  • These findings advance the understanding of spin selectivity in chiral systems.