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Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers

Theofano Panayiotou1, Stella Michael1, Apostolos Zaravinos2,3

  • 1Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus.

Plos Pathogens
|April 17, 2020
PubMed
Summary

Octamer binding transcription factor-4 (Oct4) expression in cervical cancer is linked to human papillomavirus (HPV) oncogenes. This interaction affects cancer cell growth and migration, suggesting a novel mechanism in HPV-positive cancers.

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