Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Retrieval01:12

Retrieval

354
Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
354
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

7.1K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
7.1K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

2.4K
2.4K
Conserved Binding Sites01:49

Conserved Binding Sites

1.9K
1.9K
Conserved Binding Sites01:49

Conserved Binding Sites

5.0K
Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
5.0K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

5.4K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
5.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional reserve mitigates cognitive-motor dual-task costs in older adults: insights from age, cohort, and behavioural strategies.

European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity·2026
Same author

Contrasting cognitive control in the Simon and spatial Stroop tasks regarding their interference with the control of standing balance.

Scientific reports·2026
Same author

Challenging the Biomimetic Promise 2.0: Negative Spillover of Bio-Inspired Versus Sustainability Framing on Public Perceptions of Bio-Inspired Technologies.

Biomimetics (Basel, Switzerland)·2026
Same author

Cultural differences in healthcare: An investigation using cognitive-affective mapping.

Global mental health (Cambridge, England)·2026
Same author

Continuous Hand-Arm Vibrations Do Not Interfere with Cognitive Processing.

Journal of cognition·2026
Same author

Bindings for Action: Bridging the Gap Between Theories of Procedural Working Memory and Action Control Research.

Journal of cognition·2026
Same journal

Misinformation as strategy: Epistemic consequences and the undermining of shared truth.

Trends in cognitive sciences·2026
Same journal

Geographical psychology: Spatial variation in psychological phenomena and their consequences.

Trends in cognitive sciences·2026
Same journal

Multi-brain neurofeedback: what are we training for?

Trends in cognitive sciences·2026
Same journal

The developing vocal self.

Trends in cognitive sciences·2026
Same journal

Searching beyond decrements: Attentional guidance across the adult lifespan.

Trends in cognitive sciences·2026
Same journal

Looking into working memory through micro eye movements.

Trends in cognitive sciences·2026
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.9K

Binding and Retrieval in Action Control (BRAC).

Christian Frings1, Bernhard Hommel2, Iring Koch3

  • 1Department of Cognitive Psychology, University of Trier, Trier, Germany.

Trends in Cognitive Sciences
|April 17, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces BRAC (binding and retrieval in action control), a new framework unifying diverse research on human action control. It proposes feature binding and retrieval as distinct, independently modulated processes underlying perception-action integration.

Keywords:
action controlfeature binding and episodic retrievaltop-down versus bottom-up influences

More Related Videos

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

30.6K
Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
07:22

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes

Published on: January 12, 2024

4.3K

Related Experiment Videos

Last Updated: Dec 24, 2025

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.9K
Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

30.6K
Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
07:22

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes

Published on: January 12, 2024

4.3K

Area of Science:

  • Cognitive Psychology
  • Neuroscience
  • Human Action Control

Background:

  • Human action control research is fragmented across paradigms.
  • Existing theories are often overly specific to particular experimental setups.
  • A unified framework is needed to integrate perception and action representations.

Purpose of the Study:

  • To propose BRAC (binding and retrieval in action control), an integrative framework.
  • To unify scattered findings in action control research.
  • To define binding and retrieval as functionally distinct processes.

Main Methods:

  • Conceptual framework development.
  • Literature synthesis across diverse experimental paradigms.
  • Theoretical integration of feature binding and retrieval.

Main Results:

  • BRAC (binding and retrieval in action control) integrates a wide range of findings.
  • Identifies feature binding and retrieval as core, separable processes.
  • Demonstrates independent modulation of these processes by top-down and bottom-up factors.

Conclusions:

  • BRAC offers a novel organization of action control literature.
  • Connects previously unrelated phenomena in action-related research.
  • Provides a unified perspective on perception-action integration in human action control.