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Maxillary Sinus Floor Elevation Surgery With BioOss Mixed With Enamel Matrix Derivative: A Human Randomized
Séverine Vincent-Bugnas1,2, Yves Charbit1, Mathieu Charbit1,2
1Département de parodontologie, Pôle odontologie, Centre Hospitalier Universitaire de Nice.
The Journal of Oral Implantology
|April 17, 2020
Summary
Adding enamel matrix derivative to bovine bone mineral significantly enhances new bone formation in sinus lift procedures. This bone grafting technique improves outcomes for patients needing dental implants in the posterior maxilla.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Dentistry
- Biomaterials Science
Background:
- Xenograft bone substitutes are vital for augmenting bone volume in the posterior maxilla.
- Enamel matrix derivative (Emdogain) may enhance bone healing efficiency in grafting procedures.
Purpose of the Study:
- To compare new bone formation in sinus floor augmentation using deproteinized bovine bone mineral with or without enamel matrix derivative.
- To evaluate the efficacy of enamel matrix derivative as an adjunct to bone grafting for dental implant placement.
Main Methods:
- Prospective randomized, controlled split-mouth study involving 16 patients undergoing bilateral sinus floor augmentation.
- Histomorphometric analysis of bone biopsies after 6 months to quantify newly formed bone.
- Radiographic assessment of implant survival and peri-implant bone levels up to 24 months post-loading.
Main Results:
- Significantly higher new bone formation in the group treated with deproteinized bovine bone mineral plus enamel matrix derivative (22.6%) compared to deproteinized bovine bone mineral alone (15.5%).
- No significant differences in residual graft material or connective tissue percentages between groups.
- High implant survival rates and stable peri-implant bone levels observed in both groups.
Conclusions:
- Enamel matrix derivative significantly enhances new bone formation when combined with deproteinized bovine bone mineral for sinus lift augmentation.
- This combination therapy is effective for augmenting deficient alveolar ridges, facilitating successful dental implant placement.
