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Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Venous Thrombosis I: Introduction01:30

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
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The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
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Veins of Lower Limbs01:15

Veins of Lower Limbs

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The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
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Updated: Dec 23, 2025

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Thymoma Causing Bilateral Upper Extremity Deep Vein Thrombosis.

Hoang Bui1, Jessica L Helms2, Miguel Sierra-Hoffman3

  • 1Texas A&M Detar Family Residency Program, Victoria, TX, 77901, USA.

Respiratory Medicine Case Reports
|April 18, 2020
PubMed
Summary

This case report details a rare instance of Type B2 thymoma presenting with extensive bilateral upper extremity deep vein thrombosis. This unusual presentation highlights a potential paraneoplastic syndrome associated with thymoma.

Keywords:
CT, Computed TomographyDVT, Deep vein thrombosisDeep vein thrombosisParaneoplastic syndromeThymoma

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Area of Science:

  • Oncology
  • Vascular Surgery
  • Neurology

Background:

  • Thymoma, a tumor of the thymus gland, is often associated with paraneoplastic syndromes.
  • Deep vein thrombosis (DVT) typically affects the lower extremities, with upper extremity involvement being less common.

Observation:

  • A 38-year-old male presented with symptoms of bilateral upper extremity deep vein thrombosis.
  • Imaging revealed an anterior mediastinal mass compressing major veins, and Doppler confirmed extensive venous thrombi.
  • Laboratory tests indicated acetylcholine receptor antibodies, suggestive of myasthenia gravis, though the patient was asymptomatic.

Findings:

  • Percutaneous biopsy identified a Type B2 thymoma with a predominant T-cell population.
  • This represents the first reported case of thymoma presenting with bilateral upper extremity deep vein thrombosis.

Implications:

  • This case suggests a potential paraneoplastic link between Type B2 thymoma and upper extremity deep vein thrombosis.
  • Early recognition and management of such venous thromboembolism are crucial in patients with mediastinal masses.
  • Further research may elucidate the mechanisms underlying this rare association and inform treatment strategies.