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Updated: Dec 23, 2025

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Spontaneous regression of metastatic renal cell carcinoma after cytoreductive nephrectomy: A case report
Kuniyasu Muraoka1, Yuri Nishikawa1, Tadahiro Isoyama1
1Department of Urology, Tottori Prefectural Central Hospital, 730 Ezu, Tottori, 680-0901, Japan.
Abstract:
We herein report a case involving a 59-year-old man with right lung and mediastinal lymph node metastases from renal cell carcinoma. After cytoreductive nephrectomy without neoadjuvant therapy, he achieved spontaneous regression. The regression was maintained 3 years after the operation. We immunohistochemically examined the surgical specimens and considered the possible mechanism underlying this phenomenon.
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