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Related Experiment Videos

Campylobacter cryaerophila isolated from a human.

W Tee1, R Baird, M Dyall-Smith

  • 1Campylobacter Laboratory, Fairfield Infectious Diseases Hospital, Victoria, Australia.

Journal of Clinical Microbiology
|December 1, 1988
PubMed
Summary

Campylobacter cryaerophila, a bacterium linked to animal abortions, was identified in a human stool sample. This marks the first documented instance of this pathogen in human gastrointestinal infections.

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Human Health

Background:

  • Campylobacter cryaerophila is a bacterium primarily known for its association with abortions in cattle and pigs.
  • Previous research has not documented the presence of Campylobacter cryaerophila in human clinical samples.

Purpose of the Study:

  • To report the first isolation of Campylobacter cryaerophila from a human stool specimen.
  • To characterize the isolate using various microbiological and genetic techniques.

Main Methods:

  • Biochemical reactions for initial identification of the bacterial isolate.
  • DNA-DNA hybridization and gas-liquid chromatography for confirmation.
  • Analysis of DNA base composition (G+C content).

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Main Results:

  • Campylobacter cryaerophila was successfully recovered from the stool of a patient with prolonged intermittent diarrhea.
  • The isolate's identity was confirmed through DNA-DNA hybridization and gas-liquid chromatography.
  • The G+C content of the isolate's DNA was determined to be 31.1 +/- 1 mol%.

Conclusions:

  • This study presents the first evidence of Campylobacter cryaerophila infection in a human.
  • The findings suggest Campylobacter cryaerophila may be an underrecognized cause of human gastrointestinal illness.
  • Further research is warranted to understand the epidemiology and clinical significance of Campylobacter cryaerophila in humans.