Depression in Ménière's disease: a systematic review and meta-analysis

Area of Science:

• Otolaryngology
• Neurology
• Psychiatry

Background:

• Ménière's disease is a chronic peripheral vestibular disorder.
• It is frequently associated with psychiatric conditions, particularly depression.

Purpose of the Study:

• To assess the prevalence of depression in patients diagnosed with Ménière's disease.
• To review diagnostic metrics and depression rates across multiple studies.

Main Methods:

• Systematic database searches were conducted to identify relevant studies.
• Data on depression diagnostic scales and prevalence were extracted from selected literature.

Main Results:

• Fifteen studies encompassing 6587 patients from 8 countries were analyzed.
• The overall weighted prevalence of depression was 45.9%.
• Zung's Self-Rating Depression Scale was the most commonly used diagnostic tool.

Conclusions:

• Nearly 50% of Ménière's disease patients experience depression.
• Otolaryngologists should proactively screen for and refer patients with depression.
• Addressing depression is crucial for enhancing the quality of life in Ménière's disease patients.