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Antidepressant Prescribing in England: Patterns and Costs.

Adrian H Heald1,2,3, Mike Stedman4, Mark Davies4

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This summary is machine-generated.

Antidepressant prescriptions have nearly doubled, with Selective Serotonin Reuptake Inhibitors (SSRIs) being the most common. General practices primarily prescribe SSRIs, aligning with health guidelines.

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Area of Science:

  • Pharmacology
  • General Practice
  • Public Health

Background:

  • Antidepressant (AD) prescriptions have nearly doubled in England and Wales over the last decade.
  • Understanding current prescribing patterns in general practice is crucial.

Purpose of the Study:

  • To detail the prescribing rates of various antidepressants within general practice settings.
  • To analyze prescribing behavior from April 2017 to March 2018.

Main Methods:

  • Collected monthly prescribing data from general practices.
  • Examined British National Formulary codes, prescription numbers, quantities, and costs.
  • Analyzed prescribing practices based on collated data.

Main Results:

  • 2.1 billion doses of antidepressants were prescribed to 52 million people.
  • 11% of the population took at least one antidepressant daily.
  • Selective Serotonin Reuptake Inhibitors (SSRIs) were the most prescribed class, with sertraline being the most common SSRI. Citalopram, fluoxetine, and mirtazapine were also frequently prescribed.

Conclusions:

  • Prescribing trends largely align with National Institute for Health and Care Excellence (NICE) guidelines, emphasizing SSRIs.
  • Regular audits at the general practice level are recommended for targeted and evidence-based medication use.