[COVID-19 pandemia: Impact on the cariovascular system. Data of 1^st April 2020]

Area of Science:

• Cardiology
• Infectious Diseases
• Virology

Background:

• Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes angiotensin receptors for host cell entry, a mechanism implicated in COVID-19 pneumonia.
• The virus presents a dual threat to the cardiovascular system: exacerbating infection in individuals with pre-existing cardiovascular conditions and directly inducing severe cardiovascular damage.

Purpose of the Study:

• To highlight the significant cardiovascular implications of SARS-CoV-2 infection.
• To emphasize the potential adverse cardiovascular effects of COVID-19 therapies.
• To underscore the necessity of cardiovascular protection strategies during SARS-CoV-2 infection.

Main Methods:

• Review of existing literature on SARS-CoV-2 pathogenesis and cardiovascular manifestations.
• Analysis of clinical data linking COVID-19 severity to cardiovascular comorbidities.
• Evaluation of reported cardiovascular side effects associated with COVID-19 treatments.

Main Results:

• SARS-CoV-2 infection is associated with intensified disease course in patients with cardiovascular comorbidities.
• The virus can precipitate life-threatening cardiovascular lesions.
• Therapeutic interventions for COVID-19 may pose risks to cardiovascular health.

Conclusions:

• Cardiovascular protection must be a key consideration in managing patients with COVID-19.
• Further research is warranted to develop targeted cardiovascular support during SARS-CoV-2 infection and treatment.