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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Round table: arguments in supporting abbreviated or biparametric MRI of the prostate protocol
Michele Scialpi1, Eugenio Martorana2, Pietro Scialpi3
1Section of Diagnostic Imaging, Department of Surgical and Biomedical Sciences, Santa Maria della Misericordia Hospital, University of Perugia, S. Andrea delle Fratte, 06156, Perugia, Italy. michelescialpi1@gmail.com.
Abstract:
Prostate Imaging Reporting and Data System (PI-RADS) version 2.1 update, in the attempt to improve clinical guidelines for multiparametric magnetic resonance imaging (mpMRI) of the prostate, has clear limitations. The role of dynamic contrast-enhanced sequences is not defined, precise guidance on the clinical management (biopsy or clinical surveillance) for score 3 lesions [equivocal for clinical significant prostate cancer (sPCa)] is not offered and criteria for lesions interpretation remain difficult and subjective. We report criteria and arguments in supporting the use of abbreviated or biparametric prostate MRI protocol in clinical practice for detection and management of PCa.
Insights
The Prostate Imaging Reporting and Data System (PI-RADS) v2.1 has limitations. This study supports abbreviated or biparametric prostate MRI protocols for prostate cancer detection and management.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- The Prostate Imaging Reporting and Data System (PI-RADS) version 2.1 aims to standardize multiparametric MRI (mpMRI) for prostate cancer.
- Current PI-RADS v2.1 guidelines present limitations, including undefined roles for dynamic contrast-enhanced sequences and unclear management strategies for PI-RADS 3 lesions.
Purpose of the Study:
- To address the limitations of PI-RADS v2.1.
- To present criteria supporting the use of abbreviated or biparametric prostate MRI protocols for prostate cancer detection and management.
Main Methods:
- Review and analysis of existing PI-RADS v2.1 guidelines.
- Development of criteria and arguments for abbreviated/biparametric MRI protocols.
Main Results:
- PI-RADS v2.1 has limitations in defining the role of dynamic contrast-enhanced sequences.
- Management of PI-RADS 3 lesions remains ambiguous, requiring subjective interpretation.
- Abbreviated or biparametric MRI protocols offer a viable alternative for prostate cancer assessment.
Conclusions:
- The current PI-RADS v2.1 update has significant limitations impacting clinical practice.
- Abbreviated or biparametric prostate MRI protocols show promise for improving the detection and management of prostate cancer.
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