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Published on: November 7, 2020
Novel coronavirus disease (COVID-19) in children
Hasan Tezer1, Tuğba Bedir Demirdağ2
1Department of Pediatric Infectious Disease, Faculty of Medicine, Gazi University, Ankara, Turkey
Insights
Coronavirus disease (COVID-19) is generally mild in children, but severe cases can occur, particularly in infants and those with underlying conditions. This review summarizes pediatric COVID-19 epidemiology, clinical features, diagnosis, and treatment.
Area of Science:
- Infectious Diseases
- Pediatrics
- Public Health
Background:
- Coronavirus disease (COVID-19) rapidly became a global pandemic in 2020.
- COVID-19 primarily affects the respiratory system, with varying severity in different age groups.
- While generally less severe in children, pediatric COVID-19 cases can range from asymptomatic to critical.
Purpose of the Study:
- To review the current understanding of COVID-19 in pediatric populations.
- To synthesize information on the epidemiology, clinical presentation, diagnosis, and treatment of COVID-19 in children.
- To address the knowledge gaps regarding pediatric COVID-19 patterns and management.
Main Methods:
- Literature review of published pediatric COVID-19 reports.
- Synthesis of data on epidemic trends, clinical characteristics, and diagnostic approaches.
- Compilation of information on treatment strategies for pediatric COVID-19 cases.
Main Results:
- Children represent 1-5% of diagnosed COVID-19 cases globally.
- Approximately 90% of pediatric cases are asymptomatic, mild, or moderate.
- Severe illness occurs in up to 6.7% of children, primarily those under one year or with comorbidities.
Conclusions:
- COVID-19 presents differently in children compared to adults, with a generally milder course.
- Further research is needed to fully elucidate the epidemiological and clinical patterns of COVID-19 in pediatric patients.
- Standardized diagnostic and treatment protocols for pediatric COVID-19 are essential.
Abstract:
Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6% mortality rate. This novel infectious disease causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. In older patients and/or patients with underlying conditions, it may result in acute respiratory distress syndrome, multi organ failure and even death. According to the current literature, children account approximately for 1%–5% of diagnosed COVID-19 cases. Generally, COVID-19 seems to be a less severe disease for children than adults. Approximately 90% of pediatric patients are diagnosed as asymptomatic, mild, or moderate disease. However, up to 6.7% of cases may be severe. Severe illness is generally seen in patients smaller than 1 year of age and patients who have underlying disesases. The epidemiological and clinical patterns of COVID-19 and treatment approaches in pediatric patients still remain unclear although many pediatric reports are published. This review aims to summarize the current epidemics, clinical presentations, diagnosis, and treatment of COVID-19 in pediatric patients.
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