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The association between serum 25-hydroxyvitamin D levels and dental caries in US adults
Fangjing Zhou1, Yang Zhou2, Jing Shi3
1Shanxi Medical University, Taiyuan, China.
Objectives:
We investigated whether 25-hydroxyvitamin D concentration is independently associated with dental caries among adults in the United States.
Subjects And Methods:
This investigation was a cross-sectional study. A total of 4,244 participants (aged 20-80 years) were enrolled through the 2007-2008 National Health and Nutrition Examination Survey (NHANES). Serum 25-hydroxyvitamin D was categorized into four groups based on previous studies: normal (≥75 nmol/ml), insufficient (50-74.9 nmol/ml), deficient (25-49.9 nmol/ml), and severely deficient (<25 nmol/ml). The dependent and independent variables included dental caries and serum 25-hydroxyvitamin D, respectively. The data were analyzed using univariate analyses, multivariable-adjusted analyses, and subgroup analyses.
Results:
The fully adjusted model showed that 25-hydroxyvitamin D levels were negatively associated with dental caries after adjusting for the confounders (OR = 0.93, 95% CI 0.89 to 0.98). Compared with the normal group, the likelihood of dental caries was 2.48, 1.29, and 1.43 times higher in the severely deficient, deficient, and insufficient groups, respectively.
Conclusions:
Our findings suggest that serum 25-hydroxyvitamin D levels are significantly associated with the occurrence of dental caries among US adults.
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