[Gastrin and blood proteins]

With the aid of affinic, ion-exchange- and gel-chromatography, disc- and immunoelectrophoresis, the blood serum of healthy people and animals was shown to contain proteins capable of interaction with gastrin. These proteins form a system including, along with albumins, globulins with electrophoretic mobility of alpha- and gamma-globulins. The immunoglobulins interacting with gastrin are related to the G class. Presence of a number of forms of the labile, spatially organized structural hormonal protein complexes is suggested, which play the functional part of an effective storage and transport of the hormone from the hormone-producing cell to the effector one, and excitation of its membrane's structures. Such overmolecular complexes seem to be easier recognized by the celleffector and to exert a specific action.