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Related Experiment Video

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Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
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Fetal CHD and perinatal outcomes.

Christina J Ge1, Amanda C Mahle2, Irina Burd2

  • 1Wayne State University School of Medicine, Detroit, MI, USA.

Cardiology in the Young
|April 21, 2020
PubMed
Summary

Prenatal diagnosis of congenital heart disease (CHD) is linked to earlier delivery and lower birth weight. It also increases the likelihood of cesarean section for delivery management.

Keywords:
CHDfetal anomaliesprenatalpreterm deliveryultrasound

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Area of Science:

  • Perinatal Medicine
  • Fetal Cardiology
  • Obstetrics

Background:

  • Congenital heart disease (CHD) is a common birth defect.
  • Prenatal diagnosis of CHD allows for early intervention planning.
  • Understanding delivery management for fetuses with CHD is crucial.

Purpose of the Study:

  • To evaluate delivery management and outcomes in fetuses with prenatally diagnosed CHD.
  • To compare delivery characteristics between fetuses with CHD, non-cardiac anomalies, and no anomalies.

Main Methods:

  • Retrospective cohort study of 6194 fetuses born between 2013-2016.
  • Comparison of outcomes in 170 fetuses with prenatally diagnosed CHD versus controls.
  • Primary outcomes: preterm delivery incidence and mode of delivery.

Main Results:

  • Fetuses with CHD delivered earlier (38.6 weeks) than non-anomalous controls (39.1 weeks).
  • Neonates with CHD had significantly lower birth weights.
  • A 1.5-fold increased rate of primary cesarean sections was observed in fetuses with prenatally diagnosed CHD (OR 1.49).

Conclusions:

  • Prenatal diagnosis of CHD is associated with significantly lower birth weight.
  • Preterm delivery is more common in fetuses with prenatally diagnosed CHD.
  • Increased risk of primary cesarean section delivery is linked to prenatal CHD diagnosis.