Related Experiment Video
Updated: Dec 23, 2025
09:37
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
2.8K
Lichenoid Keratosis: A Clinical Trap without Secrets for Reflectance Confocal Microscopy
Sara Mazzilli1, Terenzio Cosio1, Elena Campione1
1Dermatologic Unit, University of Rome Tor Vergata, Rome, Italy.
Case Reports in Dermatology
|April 21, 2020
Summary
Lichen planus-like keratosis can be challenging to diagnose. Reflectance confocal microscopy is a useful noninvasive tool for diagnosing difficult cases of lichen planus-like keratosis.
Area of Science:
- Dermatology
- Dermatopathology
- Optical Imaging
Background:
- Lichenoid keratosis, reclassified as lichen planus-like keratosis (LPLK), presents diagnostic challenges.
- Clinical and dermoscopic features of LPLK are often insufficient for accurate diagnosis without biopsy.
Observation:
- Two challenging cases of LPLK were encountered.
- Reflectance confocal microscopy (RCM) was utilized in both cases.
Findings:
- RCM provided valuable diagnostic information in unclear LPLK cases.
- The noninvasive nature of RCM aids in diagnosis.
Implications:
- Reflectance confocal microscopy is a promising tool for diagnosing difficult LPLK.
- Noninvasive diagnostic methods can improve patient care and reduce the need for biopsies.
More Related Videos
Related Concept Videos
01:16Confocal Fluorescence Microscopy
19.7K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
19.7K
01:14Changes in Skin Color: Clinical Perspectives
3.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.2K