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Updated: Dec 23, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
A High Recall Classifier for Selecting Articles for MEDLINE Indexing
Alastair R Rae1, Max E Savery1, James G Mork1
1Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, MD.
Abstract:
MEDLINE is the National Library of Medicine's premier bibliographic database for biomedical literature. A highly valuable feature of the database is that each record is manually indexed with a controlled vocabulary called MeSH. Most MEDLINE journals are indexed cover-to-cover, but there are about 200 selectively indexed journals for which only articles related to biomedicine and life sciences are indexed. In recent years, the selection process has become an increasing burden for indexing staff, and this paper presents a machine learning based system that offers very significant time savings by semi-automating the task. At the core of the system is a high recall classifier for the identification of journal articles that are in-scope for MEDLINE. The system is shown to reduce the number of articles requiring manual review by 54%, equivalent to approximately 40,000 articles per year.
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