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Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System

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Functional Intracardiac Paraganglioma.

Yongwoo Chung¹, Jae Woong Choi¹, Kyung-Hwan Kim¹

¹Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

The Korean Journal of Thoracic and Cardiovascular Surgery

|April 21, 2020

Summary

This summary is machine-generated.

A rare intracardiac paraganglioma was diagnosed in a 39-year-old man presenting with chest pain. Surgical removal was successful, confirming the diagnosis and highlighting the rarity of this condition.

Keywords:

Heart neoplasms Hypertension Paraganglioma

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Area of Science:

Cardiology
Oncology
Pathology

Background:

Paragangliomas are rare neuroendocrine tumors that can occur in various locations.
Intracardiac paragangliomas are exceptionally rare, posing diagnostic and therapeutic challenges.
Symptoms may include chest pain, palpitations, and headache, mimicking other cardiovascular conditions.

Observation:

A 39-year-old male presented with chest pain, palpitations, and headache.
Computed tomography revealed a large lesion (7.0 cm×6.2 cm) with features suggestive of paraganglioma.

Findings:

Histopathology confirmed the resected tumor as a paraganglioma.
Preoperative treatment with alpha- and beta-blockers facilitated surgical management.

Implications:

This case underscores the need for vigilance in diagnosing rare cardiac tumors.
Successful surgical excision and medical management offer a favorable prognosis for intracardiac paraganglioma.