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Updated: Dec 23, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
The Cloaked Intruder: An Unexpected Case of Eosinophilic Cholangitis
Shalaka Akolkar1, Jalpa Patel1, Backer Abdu1
1Division of Gastroenterology, Internal Medicine, Michigan State University-Providence Park Hospital, Southfield, MI.
Abstract:
Often, when biliary strictures are evaluated, malignancy is high on the differential. However, it is important to consider benign and malignant causes because approximately 10% of biliary strictures are benign. Eosinophilic cholangitis is an extremely rare benign disorder of the biliary tract caused by fibrosis and stricture from eosinophilic infiltration. The etiology of the disease remains unclear, and often, patients present with obstructive jaundice. We present a young man who presented with obstructive jaundice and abdominal pain, with a biliary stricture and peripheral eosinophilia. The final surgical pathology revealed eosinophilic cholangitis.
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