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Appendiceal Adenocarcinoma Associated With Ulcerative Colitis.
Fredy Nehme1, Ashley Schneider2, Fadi Hamid1
1Department of Gastroenterology and Hepatology, University of Missouri Kansas City, Kansas City, MO.
ACG Case Reports Journal
|April 21, 2020
Summary
Ulcerative colitis (UC) increases colorectal cancer risk. This case highlights a rare association between long-standing UC and appendiceal adenocarcinoma, emphasizing the need for clinical awareness.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Ulcerative colitis (UC) is a significant risk factor for colorectal cancer.
- Appendiceal adenocarcinoma is a rare malignancy, with limited established risk factors.
Observation:
- A 42-year-old patient with a history of long-standing UC presented with symptoms of acute appendicitis.
- The patient had recently undergone a routine colonoscopy.
Findings:
- Histopathological examination confirmed moderately differentiated appendiceal adenocarcinoma.
- This represents a rare complication of long-standing ulcerative colitis.
Implications:
- Clinicians should maintain a high index of suspicion for appendiceal cancer in patients with long-standing UC presenting with appendiceal symptoms.
- Increased awareness may lead to earlier diagnosis and improved outcomes for this rare condition.
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