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Phytotherapy for Cardiovascular Disease: A Bench-to-Bedside Approach
Mervin Chávez-Castillo1,2, Ángel Ortega2, Pablo Duran2
1Psychiatric Hospital of Maracaibo, Maracaibo, Venezuela
Current Pharmaceutical Design
|April 21, 2020
Summary
Medicinal herbs (MH) show potential in treating cardiovascular disease (CVD) by targeting inflammation and oxidation. Further clinical research is needed to confirm their efficacy and mechanisms for conditions like dyslipidemia, atherosclerosis, and hypertension.
Area of Science:
- Biomedical Research
- Cardiovascular Medicine
- Phytotherapy
Background:
- Cardiovascular disease (CVD) is a leading global cause of death.
- Novel therapeutic strategies for CVD are urgently needed.
- Phytotherapy, using medicinal herbs (MH), is gaining scientific interest for treating CVD.
Purpose of the Study:
- To review preclinical and clinical evidence on MH for CVD treatment.
- To explore the mechanisms of action of MH in CVD.
- To bridge the gap between laboratory findings and clinical application.
Main Methods:
- Comprehensive literature review of preclinical and clinical studies.
- Analysis of MH effects on CVD pathogenesis (dyslipidemia, atherosclerosis, hypertension).
- Evaluation of anti-inflammatory and anti-oxidant properties of MH.
Main Results:
- Numerous MH demonstrate anti-inflammatory and anti-oxidant properties.
- MH show potential in ameliorating dyslipidemia, atherosclerosis, and hypertension.
- Preclinical data is abundant, but robust clinical evidence is still developing.
Conclusions:
- Medicinal herbs offer promising therapeutic potential for cardiovascular disease.
- Further large-scale clinical trials are necessary to validate MH efficacy and safety.
- MH may represent a valuable complementary approach in CVD management.
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