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Leptomeningeal Relapse of Embryonal Rhabdomyosarcoma after 15 years
S Chew1, J P Gleeson2, A McCarthy1
1Department of Medical Oncology, St James's Hospital, Dublin 8, Ireland.
Irish Medical Journal
|April 21, 2020
Summary
This case study highlights an exceptionally rare, very late relapse of rhabdomyosarcoma (RMS) in the leptomeninges 15 years after initial treatment. It underscores the importance of long-term monitoring for childhood soft tissue tumors.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Soft Tissue Sarcomas
Background:
- Rhabdomyosarcoma (RMS) is the most common childhood soft tissue malignancy.
- Late relapses of RMS can occur, but recurrences beyond 10 years are exceedingly rare.
- Leptomeningeal metastasis is a serious complication of RMS.

