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Emerging Features of Linear Motif-Binding Hub Proteins

Nathan Jespersen1, Elisar Barbar1

  • 1Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.

Trends in Biochemical Sciences
|April 21, 2020
PubMed
Summary

Hub proteins connect cellular systems. This study introduces a new class, linear motif-binding hubs (LMB-hubs), exemplified by dynein light chain LC8, offering a residue-level framework for their function.

Keywords:
LC8dynamicfeedback regulationhubslinear motifs

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