Cerebral angiography using transauricular access in a rabbit model: a new technique

Area of Science:

• Interventional Radiology
• Animal Models
• Vascular Imaging

Background:

• Cerebral angiography in rabbit models is crucial for interventional radiology research.
• Conventional femoral artery access requires technically challenging surgical cutdown.
• A minimally invasive alternative is needed for improved procedural efficiency.

Purpose of the Study:

• To evaluate a novel transauricular cerebral angiography technique in a rabbit model.
• To assess the feasibility and efficacy of accessing cerebral vasculature via the ear.
• To establish a simpler method for angiographic studies in rabbits.

Main Methods:

• Ten rabbits underwent central auricular artery puncture using 20-gauge i.v. catheters.
• A 2.0 F microcatheter and 0.016-inch guide wire were advanced to the aortic arch.
• Selective angiography of cerebral arteries was performed using the transauricular approach.

Main Results:

• Successful puncture of central auricular arteries was achieved in all rabbits.
• Microcatheters were advanced to cerebral arteries, enabling angiography.
• A looping technique within the cardiac chamber resolved difficulties in selecting carotid arteries.

Conclusions:

• Transauricular cerebral angiography is a feasible technique for rabbit brain and carotid intervention studies.
• Vertebral angiography is achievable using the transauricular approach with a looping technique.
• The ear chosen for puncture does not impact the success of the procedure.