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Remote Laboratory Management: Respiratory Virus Diagnostics
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Development of a Mobile Laboratory for Sudden Onset Disasters.

Ian Marr1, Joshua R Francis2,3, Dianne P Stephens1,3

  • 1National Critical Care and Trauma Response Centre, Darwin, Australia.

Disaster Medicine and Public Health Preparedness
|April 22, 2020
PubMed
Summary

A mobile diagnostic laboratory was developed for disaster response, significantly improving clinical diagnostics in sudden onset disasters. This system offers rapid setup and broad diagnostic capabilities for emergency medical teams (EMTs).

Keywords:
diagnosticsdisasterinfectionlaboratorymobile

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Area of Science:

  • Disaster medicine
  • Clinical diagnostics
  • Mobile laboratory systems

Background:

  • Clinical diagnostics are historically limited in sudden onset disasters.
  • Emergency medical teams (EMTs) require enhanced field diagnostic capabilities.

Purpose of the Study:

  • To design, implement, and evaluate a mobile diagnostic laboratory for type 2 EMT field hospitals.
  • To assess the feasibility and effectiveness of advanced diagnostic platforms in austere environments.

Main Methods:

  • Reviewed and selected diagnostic platforms based on field needs, including HemoCue, i-STAT, BIOFIRE FILMARRAY multiplex rt-PCR, microscopy, and rapid tests.
  • Conducted trials in Katherine, Australia, and Dili, Timor-Leste.

Main Results:

  • Successful evaluation of FilmArray panels for blood culture, gastrointestinal, and respiratory infections.
  • Validated HemoCue hemoglobin and WBC DIFF against laboratory standards with high correlation.
  • Identified 117 pathogens using FilmArray in Timor-Leste, including significant findings in blood cultures and cerebrospinal fluid.

Conclusions:

  • The mobile laboratory significantly advances diagnostic capabilities in sudden onset disasters.
  • Rapid setup (<24 hr) and deployment are key advantages.
  • Future deployments with EMT2 will enhance diagnostic capacity in fragmented health systems.