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Galectin-3 regulates UVB-induced inflammation in skin

Jen-Yu Wang1, Po-Hsuan Lu2, Wan-Wan Lin3

  • 1Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Mackay Junior College of Medicine, Nursing, and Management, New Taipei City, Taiwan.

Journal of Dermatological Science
|April 22, 2020
PubMed
Summary

Galectin-3 promotes skin inflammation following UVB exposure. Reducing galectin-3 in skin cells and mice lessens UVB-induced damage and inflammatory markers, suggesting a therapeutic target for UV-related skin conditions.

Keywords:
Caspase-1Galectin-3IL-1βInflammasomeKeratinocyteUV

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