Related Experiment Video
Updated: Dec 23, 2025

07:06
Combining Imaging and Electrophysiology to Visualize and Record Spreading Depolarizations in Mice
Published on: October 4, 2024
837
Correction to: Linking demyelination to compound action potential dispersion with a spike-diffuse-spike approach
Richard Naud1,2, André Longtin3
1Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada. rnaud@uottawa.ca.
Journal of Mathematical Neuroscience
|April 22, 2020
Summary
This study corrects a factual error in a previously published paper regarding altered propagation dynamics in mathematical neuroscience. The correction ensures accuracy in the scientific record for future research.
Area of Science:
- Mathematical Neuroscience
- Computational Biology
- Biophysics
Context:
- The original article investigated altered propagation dynamics.
- A specific error was identified in the first paragraph of the "Altered propagation" section.
- This correction pertains to the foundational understanding of signal propagation in neural models.
Purpose:
- To rectify a factual inaccuracy in the published work.
- To ensure the scientific integrity and reproducibility of research in mathematical neuroscience.
- To provide a corrected reference for altered propagation mechanisms.
Summary:
- A correction is issued for a mistake found in the "Altered propagation" section of a prior publication.
- The identified error impacts the description of signal propagation dynamics.
- This erratum ensures the accuracy of the original article's findings.
Impact:
- Enhances the reliability of the scientific literature in mathematical neuroscience.
- Prevents potential misinterpretations or errors in subsequent studies citing the original work.
- Supports accurate modeling and understanding of neural signal propagation.
Related Concept Videos
Propagation of Action Potentials
8.5K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
8.5K
Action Potentials
140.5K
Overview
140.5K
Action Potential
10.4K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
10.4K
Action Potential
4.1K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
4.1K
Integration of Synaptic Events
3.3K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
3.3K
The Role of Ion Channels in Neuronal Computation
3.5K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.5K

