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Updated: Dec 23, 2025

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Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair
Published on: February 17, 2021
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Human Wound Healing Ex Vivo Model with Focus on Molecular Markers
Jennifer Gherardini1, Max van Lessen1, Ilaria Piccini1
1Monasterium Laboratories, Skin and Hair Research Solutions, Muenster, Germany.
Methods in Molecular Biology (Clifton, N.J.)
|April 22, 2020
Abstract:
Wound healing is a complex, multifactorial process that is divided in sequential and overlapping phases in order to restore the skin barrier. For the study of wound healing, different in vivo, in vitro, and ex vivo models have been used in the past. Here we describe in detail the methodology of the human skin punch-in-a-punch ex vivo wound healing model.

