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Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste
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Recent advances in polyhydroxyalkanoate production: Feedstocks, strains and process developments.

Mengxing Li1, Mark R Wilkins2

  • 1Department of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln 68583, USA; Department of Statistics, University of Nebraska-Lincoln, Lincoln 68583, USA.

International Journal of Biological Macromolecules
|April 22, 2020
PubMed
Summary

Polyhydroxyalkanoates (PHAs) can be produced cost-effectively using abundant waste materials like lignocellulosic biomass. This research reviews strains and processes for sustainable PHA production from low-cost feedstocks.

Keywords:
PHAcheap feedstockslignocellulosic feedstocksprocess developmentstrains

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Area of Science:

  • Biotechnology and Industrial Microbiology
  • Polymer Science
  • Sustainable Materials

Background:

  • Polyhydroxyalkanoates (PHAs) are biodegradable polymers with properties rivaling petroleum plastics and excellent biocompatibility.
  • High production costs, primarily due to expensive feedstocks, hinder the commercialization of PHAs.
  • Reducing feedstock costs is crucial for making PHA production economically viable.

Purpose of the Study:

  • To explore the use of low-cost waste materials, specifically lignocellulosic biomass, as feedstocks for Polyhydroxyalkanoates (PHA) production.
  • To review microbial strains capable of converting these alternative feedstocks into PHAs.
  • To elaborate on process development, including fermentation and downstream processing, for efficient PHA synthesis.

Main Methods:

  • Literature review of microbial strains involved in PHA production from various waste materials.
  • Emphasis on newly isolated strains with potential for utilizing lignocellulosic biomass.
  • Analysis of factors influencing PHA yield, fermentation strategies, and downstream purification processes.

Main Results:

  • Lignocellulosic biomass and other waste materials are identified as promising, cost-effective feedstocks for PHA synthesis.
  • A review of existing and newly isolated microbial strains highlights their capability in converting these feedstocks.
  • Key factors affecting PHA production efficiency and downstream processing are discussed, providing insights for process optimization.

Conclusions:

  • Utilizing waste materials, particularly lignocellulosic biomass, significantly reduces feedstock costs for Polyhydroxyalkanoates (PHA) production.
  • The development and selection of appropriate microbial strains are critical for efficient conversion of these low-cost feedstocks.
  • Further process development in fermentation and downstream processing is essential for the cost-effective commercialization of PHAs.