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Updated: Dec 23, 2025

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
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Variable Assembly of EMRE and MCU Creates Functional Channels with Distinct Gatekeeping Profiles

Riley Payne1, Carmen Li1, J Kevin Foskett2

  • 1Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Iscience
|April 22, 2020
PubMed
Summary

Most mitochondrial calcium channels (MCU) function with two EMRE subunits, not four, regulating calcium influx. Varying EMRE levels fine-tune channel activity and gatekeeping in cells.

Keywords:
Molecular BiologyMolecular Structure

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