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Updated: Dec 23, 2025

Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus
Published on: July 27, 2021
Coronavirus disease 2019: reassembly attack of coronavirus
Chenglei Yang1, Xue Qiu2, Haoran Fan2
1Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi Province, PR China.
Insights
The Coronavirus Disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to a global health emergency. This article reviews COVID-19 trends, epidemiology, and control measures for global epidemic prevention.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- The world has experienced three major coronavirus outbreaks in the last two decades.
- Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, emerged in Wuhan, China, and rapidly became a global pandemic.
- As of March 17, 2020, COVID-19 caused over 179,000 cases and 7,400 deaths globally, with no approved treatment or vaccine.
Purpose of the Study:
- To summarize the worldwide epidemic trend of COVID-19.
- To discuss the epidemiological characteristics of SARS-CoV-2.
- To review prevention and control measures for global epidemic management.
Main Methods:
- Review of worldwide epidemic data for COVID-19.
- Analysis of epidemiological characteristics of SARS-CoV-2 transmission.
- Compilation of current prevention and control strategies.
Main Results:
- COVID-19 spread rapidly across 163 countries, causing a major public health emergency.
- The virus, SARS-CoV-2, originated in bats and exhibits efficient human-to-human transmission.
- A global mortality rate of 4.1% was observed among confirmed cases.
Conclusions:
- Effective treatment and vaccines for COVID-19 are still lacking.
- Isolating the source of infection and blocking transmission routes are critical.
- The article aims to provide valuable experience and insights for global epidemic prevention and control efforts.
Abstract:
There have been three major global outbreaks of acute respiratory disease caused by coronavirus in the last two decades. The ongoing Coronavirus Disease 2019 (COVID-19) first emerged in Wuhan, China, is the most dangerous, which spread to 163 countries and 6 continents and caused a major public health emergency worldwide. The outbreak is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) originated from bats, which spreads rapidly from human to human. As of 17 March 2020, there have been 179,112 confirmed cases and 7426 deaths worldwide, with a mortality rate of 4.1%. There is currently no effective treatment or approved vaccine, so isolating the source of infection and blocking the routes of transmission is important. In this article, we summarized the worldwide epidemic trend of COVID-19 and discussed its epidemiological characteristics, prevention and control measures. We hope this article could provide experience and help for global epidemic prevention and control.
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