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Updated: Dec 23, 2025

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Forward Programming of Pluripotent Stem Cells to Neurons.

Jinchao Gu1, Brett Cromer1, Huseyin Sumer1

  • 1Department of Chemistry and Biotechnology, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Australia.

Current Molecular Medicine
|April 23, 2020
PubMed
Summary

Directly programming pluripotent stem cells (PSCs) using transcription factors offers a faster, purer method for generating specific neuronal subtypes, bypassing traditional multi-step differentiation for studying developmental biology and diseases.

Keywords:
Embryonic stem cellsNeuronal differentiationNeuronsPluripotent stem cellsProgrammingTranscription factor

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