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Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Published on: June 16, 2020

Multiple sclerosing pneumocytomas: a review.

Prodipto Pal^1,2, Runjan Chetty^3,2

¹Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada prodipto.pal@uhn.ca.

Journal of Clinical Pathology

|April 23, 2020

Summary

This summary is machine-generated.

Multiple sclerosing pneumocytomas (SP), a rare lung tumor, are exceptionally uncommon. This review details their rare presentation, pathology, and proposes a novel classification for multiple SP distribution.

Keywords:

histopathology lung pulmonary pathology surgical pathology

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Area of Science:

Pulmonology
Oncology
Pathology

Background:

Sclerosing pneumocytoma (SP) is a rare, benign lung tumor typically presenting as solitary nodules.
Multiple SP are exceedingly rare, with limited literature available.

Purpose of the Study:

To review the literature on multiple SP.
To discuss clinical presentations, histopathology, differential diagnoses, and molecular pathogenesis.
To propose a classification for the distribution of multiple SP.

Main Methods:

Literature review of multiple SP cases.
Analysis of clinical, radiological, and pathological findings.
Review of molecular pathogenesis, including AKT-1 pathways.

Main Results:

Multiple SP share similar histological patterns and can affect any lung lobe bilaterally.
SP shows a predilection for non-smoking East Asian females.
Common symptoms include cough and hemoptysis; chest pain may occur with pleural involvement.

Conclusions:

Multiple SP, though rare, present with diverse distributions and histological patterns.
Understanding the molecular pathogenesis, particularly AKT-1 pathways, is crucial.
A proposed classification aids in characterizing the distribution of multiple SP.