[Comparison of Efficacy between Thrombelastography and Conventional Coagulation Tests and Analysis of Their...

To assess the coagulation state of patients with abnormal coagulation function by thrombelastography (TEG) and conventional coagulation tests (CCT) and to estimate their correlations in determining the blood coagulation.

A total of 150 patients with abnormal coagulation function were enrolled, standard coagulation tests were assessed for the patients. At the same time, the thrombelastographic test was performed with TEG after sample recalcification with kaolin activator.

There were correlations between the TEG and CCT. PT and APTT positively correlated with the R time (r=0.296, r=0.369, P＜0.01), the R time negatively correlated with the Fib (r=-0.257, P＜0.01), K negatively correlated with the Fib (r=0.509, P＜0.01), K positively correlated with the TT (r=0.318, P＜0.01), Angle positively correlated with the Fib (r=0.506, P＜0.01) and negatively correlated with the TT (r=-0.237, P＜0.05). CI negatively correlated with the PT (r=-0.236, P＜0.05). The sensitivity to detect hypocoagulable state estimated with TEG parameter R was higher than that with PT and Fib (P＜0.01), respectively. The sensitivity to hypocoagulable state estimated with K and Angle was higher than that with Fib and TT, respectively (P＜0.01).

There are significant correlation between some parameters of the TEG and conventionnal coagulation tests, however, the consistency and sensitivity of the two methods are poor, two methods can not be replaced by each other.