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Related Experiment Video

Updated: Dec 23, 2025

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
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Parkinson's Disease and Headaches: A Cross-Sectional Study.

Pedro Augusto Sampaio Rocha-Filho1,2, Carlos Frederico Leite Souza-Lima3

  • 1Department of Neuropsychiatry, Universidade Federal de Pernambuco (UFPE), Recife, Brazil.

Headache
|April 23, 2020
PubMed
Summary

Headaches are common in Parkinson's disease (PD) patients, but this study found no link between headache severity and PD motor symptoms. Further research is needed to understand headache causes in PD.

Keywords:
Parkinson diseaseheadachemigraine disordersmuscle rigiditypaintension-type headache

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Area of Science:

  • Neurology
  • Pain Medicine
  • Parkinson's Disease Research

Background:

  • Parkinson's disease (PD) affects a significant portion of patients with pain, ranging from 40% to 83%.
  • Headaches are a prevalent but understudied symptom in the PD population.

Purpose of the Study:

  • To investigate the occurrence of headaches in Parkinson's disease patients.
  • To determine any correlation between motor symptom severity and headache characteristics in PD patients.

Main Methods:

  • A cross-sectional study involving consecutive Parkinson's disease patients.
  • Utilized semi-structured interviews, Epworth Sleepiness Scale, Hospital Anxiety and Depression Scale, Unified Parkinson's Disease Rating Scale (UPDRS) Part III, and Hoehn and Yahr scale.

Main Results:

  • Out of 46 patients, 43 experienced headaches (93%), with 26% reporting migraines and 67% tension-type headaches.
  • No significant association was found between headache frequency or intensity and PD stage (Hoehn and Yahr scale) or UPDRS motor scores.
  • Neck stiffness also showed no correlation with headache frequency or intensity.

Conclusions:

  • This study indicates no direct association between headaches and Parkinson's disease motor symptoms in the studied sample.
  • The findings suggest that headaches in PD patients may stem from factors independent of motor disease progression.