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Select Epstein-Barr Virus-Associated Digestive Tract Lesions for the Practicing Pathologist
Zainab I Alruwaii1, Elizabeth A Montgomery2
1From the Department of Pathology, Regional Laboratory and Blood Bank, Eastern Province, Dammam, Saudi Arabia (Alruwaii).
Archives of Pathology & Laboratory Medicine
|April 23, 2020
Summary
Epstein-Barr virus (EBV) is linked to various digestive diseases. Recognizing these EBV-associated conditions is crucial for effective clinical management and potential therapy prediction.
Area of Science:
- Gastroenterology
- Virology
- Oncology
Background:
- Epstein-Barr virus (EBV) is a common oncogenic virus.
- Over five decades, EBV has been associated with numerous neoplastic and nonneoplastic diseases.
- Several EBV-associated conditions impact the digestive system, varying in severity.
Purpose of the Study:
- To review the clinicopathologic features of recently identified EBV-related digestive conditions.
- To discuss the therapeutic implications of these emerging EBV-associated gastrointestinal lesions.
Main Methods:
- A review of published peer-reviewed literature was conducted.
Main Results:
- The study focuses on newly or recently recognized EBV-related conditions in the digestive tract.
- These conditions present a spectrum from inflammatory to severe diseases.
Conclusions:
- Recognizing these EBV-associated gastrointestinal lesions is vital for patient care.
- These lesions can influence direct clinical management strategies.
- They may also serve as predictive markers for therapeutic response.
