Related Experiment Video
Updated: Dec 23, 2025

06:50
Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
Published on: December 24, 2013
29.6K
Children with neurodegenerative disease and obsessive-compulsive behaviour
Summary
Obsessive-compulsive disorder (OCD) can affect children with neurodegenerative diseases. Combined treatment with sertraline and exposure and response prevention therapy (ERP) effectively reduced compulsive behaviors in a child with neurodegenerative disease.
Area of Science:
- Pediatric Neurology
- Child Psychiatry
Background:
- Neurodegenerative diseases in children lead to progressive skill loss and psychiatric symptoms.
- Obsessive-compulsive disorder (OCD) is a treatable condition, but its efficacy in children with neurodegenerative diseases is not well-established.
Purpose of the Study:
- To investigate the occurrence and treatment of obsessive-compulsive disorder (OCD) in a child with a neurodegenerative disease.
- To assess the effectiveness of combined medical and psychological treatments for OCD in this population.
Main Methods:
- A case study of a child with an uncommon neurodegenerative disease presenting with OCD symptoms.
- Treatment involved sertraline and adapted exposure and response prevention therapy (ERP) with significant parental involvement.
Main Results:
- The child met diagnostic criteria for OCD with predominantly compulsive acts.
- After six months of combined treatment, compulsive behaviors were resolved.
Conclusions:
- Obsessive-compulsive disorder (OCD) can manifest in children with neurodegenerative diseases.
- Combined sertraline and adapted ERP treatment demonstrated effectiveness in managing OCD symptoms in this case.
More Related Videos
Related Concept Videos
Obsessive-Compulsive Disorder
410
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
410
Personality Disorders: Dependent and Obsessive-Compulsive
297
Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...
297
Operant Conditioning Intervention
378
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
In operant conditioning, behaviors that are...
378
Attention-Deficit/Hyperactivity Disorder
652
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
652
Oppositional Defiant Disorder
500
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
500
Anxiety: Overview
781
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
781

