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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Related Experiment Video

Updated: Dec 23, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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Current radiotherapy techniques in NSCLC: challenges and potential solutions.

Niccolò Giaj-Levra1, Paolo Borghetti2, Alessio Bruni3

  • 1Advanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Italy.

Expert Review of Anticancer Therapy
|April 24, 2020
PubMed
Summary

Technological advancements in radiotherapy, including image-guided radiotherapy (IGRT) and stereotactic body radiotherapy (SBRT), are improving non-small cell lung cancer (NSCLC) treatment accuracy and outcomes. Future innovations like proton therapy and MR-Linac show promise for further enhancing NSCLC management.

Keywords:
NSCLCimrtmr-Linacprotonsradiotherapysbrttechnology

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Area of Science:

  • Radiation oncology
  • Medical physics
  • Thoracic oncology

Background:

  • Radiotherapy is a cornerstone in non-small cell lung cancer (NSCLC) management.
  • Technological advancements like image-guided radiotherapy (IGRT) have enhanced treatment precision and tolerability.

Purpose of the Study:

  • To review current technological opportunities in NSCLC radiotherapy.
  • To discuss future prospects and innovative approaches in NSCLC management.

Main Methods:

  • Review of technological advancements in radiotherapy for NSCLC.
  • Analysis of current and emerging treatment modalities.
  • Expert opinion on clinical applications and outcomes.

Main Results:

  • Stereotactic body radiotherapy (SBRT) is standard for inoperable NSCLC and shows promise for oligometastatic disease.
  • Improved accuracy and organ-at-risk sparing contribute to better treatment quality and survival.
  • Emerging technologies like proton/carbon ion therapy and MR-Linac are under investigation.

Conclusions:

  • Technological progress is significantly improving NSCLC radiotherapy outcomes.
  • SBRT and combined approaches are expanding treatment options.
  • Novel technologies like MR-Linac and particle therapy represent the future of NSCLC radiation management.