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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Pneumonia II: Pathophysiology01:29

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The pathophysiology of pneumonia involves the following steps:
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Cystic Fibrosis: Pathogenesis01:23

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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COVID-19: an Immunopathological View.

Kamran Kadkhoda1

  • 1Immunopathology Laboratory, Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA kadkhok@ccf.org.

Msphere
|April 24, 2020
PubMed
Summary

Understanding the immune mechanisms of COVID-19 is crucial for effective treatment and vaccine development. Research into the immunopathology of SARS-CoV-2 aids in managing the pandemic and preventing future outbreaks.

Area of Science:

  • Immunology
  • Virology
  • Public Health

Background:

  • The novel coronavirus disease 2019 (COVID-19) rapidly became a global pandemic.
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits high infectivity and mortality.
  • Understanding the underlying immunopathology is critical for pandemic response.
Keywords:
COVID-19SARS-CoV-2immunopathology

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