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Updated: Dec 23, 2025

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Bcl11 Transcription Factors Regulate Cortical Development and Function

Ruth Simon1, Christoph Wiegreffe1, Stefan Britsch1

  • 1Institute of Molecular and Cellular Anatomy, Ulm University, Germany.

Frontiers in Molecular Neuroscience
|April 24, 2020
PubMed

Keywords:
Bcl11aBcl11bbrain developmenthippocampusneocortexneural circuitryneurological disorderstranscription factors

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Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
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