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Related Concept Videos

Infection01:20

Infection

11.4K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
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Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.1K
Stages of Infection01:26

Stages of Infection

64.5K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
64.5K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

640
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

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[Infections as oncologic emergencies].

Andreas Edwin Juarso1, Malte Kiehl1, Markus Buchholz1

  • 1Klinik für Innere Medizin, Hämatologie, Onkologie, Stammzelltransplantation und Palliativmedizin, Evangelisches Klinikum Bethel, Schildescher Str. 99, 33611 Bielefeld, Deutschland.

Wiener Klinisches Magazin : Beilage Zur Wiener Klinischen Wochenschrift
|April 24, 2020
PubMed
Summary

Cancer patients, especially those with hematologic malignancies, face high risks of infections and treatment complications. Early recognition and empiric broad-spectrum antibiotic treatment are crucial for managing neutropenic fever and other life-threatening infections in this vulnerable population.

Keywords:
CNS infectionsHematologic neoplasmsImmunosuppressionMucositisNeutropenic feverSepsis

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Ex Vivo Infection of Live Tissue with Oncolytic Viruses
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Area of Science:

  • Oncology
  • Infectious Diseases
  • Hematology

Context:

  • Rising cancer incidence and prevalence in Germany.
  • Increasing age, comorbidities, and frailty in cancer patients necessitate multidisciplinary care.
  • Modern cancer treatments improve survival but can increase risks of complications.

Purpose:

  • To discuss potentially life-threatening infections in immunocompromised cancer patients.
  • To highlight the challenges in differentiating infections from treatment complications.
  • To emphasize the need for early recognition and management strategies.

Summary:

  • Neutropenic fever is the most common oncologic infectious emergency.
  • Early empiric broad-spectrum antibiotic therapy is essential for vulnerable cancer patients.
  • Escalated diagnostic strategies are required for successful treatment.

Impact:

  • Improved management of severe infections in cancer patients.
  • Reduced mortality and morbidity associated with infections in oncology.
  • Enhanced understanding of infection risks and complications in immunocompromised individuals.