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Updated: Dec 23, 2025

Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis
Published on: September 23, 2025
Tranquilizer effect on the Lyapunov exponents of lame horses
J Zhao1, D B Marghitu1, J Schumacher2
1Department of Mechanical Engineering, 1418 Wiggins Hall, Auburn University, Auburn, AL, 36849, USA.
Abstract:
Tranquilization of horses with acepromazine has been used to suppress erratic head movements and increase the accuracy of a lameness examination. Some equine clinicians believe that tranquilization with acepromazine will make lameness more evident by causing the horse to focus on adjusting its gait to avoid limb pain rather than its surroundings. The aim of this study was to investigate the effect of acepromazine on the Lyapunov exponents of lame horses. Ten lame horses were trotted in a straight line for a minimum of 25 strides. Kinematic data created by head movement were analyzed. Nonlinear analysis methods were applied to lame horse locomotion. The effect of acepromazine on the largest Lyapunov exponents of the lame horses were investigated. There was no statistically significant effect of acepromazine on the maximum value of Lyapunov exponents. The nonlinear dynamic methods can be used to analyze the gait in horses. Local stability of horse gait remains unchanged after the administration of acepromazine.
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