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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Dec 23, 2025

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
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Hypopyon following selective laser trabeculoplasty.

Lisa R Koenig1, Kyle D Kovacs1, Mrinali P Gupta1

  • 1Weill Cornell Medical College, Department of Ophthalmology, New York, NY, United States.

American Journal of Ophthalmology Case Reports
|April 24, 2020
PubMed
Summary

Selective laser trabeculoplasty (SLT) can rarely cause hypopyon, an inflammatory eye condition. This case highlights the importance of considering non-SLT causes for post-procedure complications.

Keywords:
HypopyonSelective laser trabeculoplasty

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Area of Science:

  • Ophthalmology
  • Glaucoma Management
  • Laser Therapy

Background:

  • Selective laser trabeculoplasty (SLT) is a common procedure for managing primary open-angle glaucoma.
  • While generally safe, potential adverse events associated with SLT require ongoing monitoring and reporting.

Observation:

  • An 85-year-old woman developed hypopyon, trabeculitis, and corneal edema after routine SLT.
  • Symptoms included post-procedural pain and decreased vision.
  • Initial treatment involved corticosteroids and empirical antiviral therapy.

Findings:

  • The patient's hypopyon and associated symptoms resolved with medical treatment.
  • No underlying inflammatory intraocular disease was identified.
  • This represents a rare instance of hypopyon following SLT without prior inflammatory history.

Implications:

  • SLT, despite its safety profile, can be associated with rare complications necessitating intervention.
  • Physicians should investigate potential causes of hypopyon unrelated to SLT, even in the absence of known risk factors.
  • This case underscores the need for vigilance regarding unusual post-SLT presentations.