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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Inhaled Medications

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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Paediatric asthma deaths in Ireland: 2006-2016.

Sarah C Richardson1, Aisling M O'Riordan2, Barry Linnane3,4

  • 1Respiratory Department, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland. sarah.richardson@cuh.ie.

Irish Journal of Medical Science
|April 24, 2020
PubMed
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Childhood asthma deaths are rare in Ireland, with most fatal cases presenting suddenly. Improved education on recognizing severe asthma symptoms and using personalized asthma action plans is crucial for prevention.

Keywords:
AdolescenceAsthmaAsthma exacerbationsAsthma mortalityPaediatrics

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Area of Science:

  • Pediatric Pulmonology
  • Public Health Research
  • Mortality Auditing

Background:

  • Asthma is the most prevalent chronic illness in childhood.
  • Childhood asthma mortality is infrequent but significant.
  • No prior national review of pediatric asthma deaths in Ireland existed.

Observation:

  • A 10-year retrospective review of pediatric asthma mortality was conducted in Ireland.
  • Data was sourced from the National Paediatric Mortality Register (NPMR).
  • Eleven cases of asthma-related childhood mortality were identified.

Findings:

  • The median age of death was 11.8 years.
  • All fatal cases presented to the Emergency Department (ED) in asystole.
  • Fifty percent experienced acute symptoms before the fatal event.
  • None of the deceased children were under secondary care.
  • Only 60% possessed a written personalized asthma action plan (PAAP).

Implications:

  • Most pediatric asthma deaths occur unexpectedly with minimal warning signs.
  • Enhanced public and patient education on recognizing severe asthma exacerbations is vital.
  • Widespread adoption and adherence to personalized asthma action plans (PAAP) are necessary to reduce mortality.