Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pneumothorax-I01:26

Pneumothorax-I

1.0K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
1.0K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

911
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
911
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

456
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
456
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

661
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
661
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

421
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
421
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

709
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
709

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Title: Abdominal Wall Necrotizing Fasciitis in a Preemie: A Case Report of a Fulminant Course.

Case reports in infectious diseases·2026
Same author

Molecular Springs in Dynamic Covalent Polymer Networks.

Macromolecules·2026
Same author

Redefining the Limits: Atom Transfer Radical Polymerization of Vinyl Ketone Monomers under Light.

ACS macro letters·2026
Same author

Mechanisms of Chiral Induction to Foldamer Backbones.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Beyond the Flare: A Case of Systemic Lupus Erythematosus Complicated by Hemophagocytic Lymphohistiocytosis.

Cureus·2025
Same author

MIS-C Like Features in a Patient of Atypical Kawasaki Disease: A Case Report.

JNMA; journal of the Nepal Medical Association·2024
Same journal

Foreign Body Migration from Subglottis to Bronchus in a Tracheostomised Child: A Case Report.

JNMA; journal of the Nepal Medical Association·2026
Same journal

Validation of the Nepalese Version of the Quality of Recovery-15 Questionnaire in Patients Undergoing Elective Surgery.

JNMA; journal of the Nepal Medical Association·2026
Same journal

Evaluation of Preference of Pain Scale in Children using Novel Animated Emoji Scale in Nepal: An Observational Study.

JNMA; journal of the Nepal Medical Association·2026
Same journal

Mucinous Ovarian Cancer in a Young Woman: A Case Report.

JNMA; journal of the Nepal Medical Association·2026
Same journal

Conundrum of Cholesterol Management and Health Implications of Low Cholesterol Levels: A Narrative Review.

JNMA; journal of the Nepal Medical Association·2026
Same journal

Clinical Profile and Management of Pleural Effusion at Tertiary Hospital of Nepal: An Observational Study.

JNMA; journal of the Nepal Medical Association·2026
See all related articles

Related Experiment Video

Updated: Dec 23, 2025

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.2K

Severe Birth Asphyxia without Sequelae: A Case Report.

Sujata Dahal1, Roshan Lama1, Nita Lohala2

  • 1Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|April 24, 2020
PubMed
Summary
This summary is machine-generated.

Perinatal asphyxia, a major cause of neonatal issues, can lead to hypoxic-ischemic encephalopathy. This case highlights a preterm infant

More Related Videos

A Swine Model of Neonatal Asphyxia
10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

14.7K
A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation
10:55

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

2.2K

Related Experiment Videos

Last Updated: Dec 23, 2025

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.2K
A Swine Model of Neonatal Asphyxia
10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

14.7K
A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation
10:55

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

2.2K

Area of Science:

  • Neonatology
  • Perinatal Medicine
  • Pediatric Neurology

Background:

  • Perinatal asphyxia is a significant contributor to neonatal morbidity and mortality.
  • It frequently results in neurodevelopmental delays, notably hypoxic-ischemic encephalopathy (HIE).

Observation:

  • A preterm male infant (1670g, 31+3 weeks gestation) was born via vaginal delivery following umbilical cord prolapse.
  • The neonate presented with absent heart rate and cyanosis, necessitating immediate resuscitation per Neonatal Advanced Life Support 2015 guidelines.
  • Despite extensive resuscitation efforts, including intubation and medication, the infant's heart rate remained critically low for two hours before spontaneous crying occurred.

Findings:

  • The case illustrates a severe presentation of birth asphyxia complicated by umbilical cord prolapse in a preterm infant.
  • Prolonged resuscitation was required, underscoring the challenges in managing such critical neonatal cases.
  • Delayed improvement in heart rate and delayed spontaneous crying were key clinical observations.

Implications:

  • This case emphasizes the critical importance of prompt and advanced resuscitation in neonates experiencing severe birth asphyxia.
  • It highlights the potential for delayed recovery even with comprehensive interventions.
  • Understanding such cases is crucial for improving management protocols for hypoxic-ischemic encephalopathy and optimizing outcomes for affected newborns.