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A forensic case of erosive cystitis and septic pulmonary embolism: is there a correlation?
F Cordasco1, F Sicilia1, M A Sacco1
1Institute of Legal Medicine, University "Magna Graecia" of Catanzaro, Italy.
Abstract:
Septic pulmonary embolism (SPE) is an uncommon disease in which a microorganism- containing thrombus causes an inflammatory reaction and a mechanical obstruction in the vascular system of the lungs. Usually it is associated with tricuspid valve vegetation, septic thrombophlebitis or infected venous catheters. We present a rare and fatal case of massive septic pulmonary thromboembolism occurred in a diabetic woman, who complained in previous days dyspnoea, abdominal pain and nausea. Autopsy findings showed evidence of an erosive cystitis, while lungs examination showed total occlusion of pulmonary circulation system due to thrombo-embolic clots. In literature cases report about an association between septic pulmonary thromboembolism and erosive cystitis haven't been reported. So, we here show the first reported fatal case of a septic pulmonary thromboembolism as a lethal evolution of an erosive cystitis.
Insights
Septic pulmonary embolism (SPE) is a rare lung condition. This case highlights a fatal instance linked to erosive cystitis, a previously unreported association.
Area of Science:
- Medicine
- Pathology
- Cardiology
Background:
- Septic pulmonary embolism (SPE) involves microorganism-laden clots obstructing lung vasculature.
- Commonly associated with tricuspid valve issues, septic thrombophlebitis, or infected catheters.
Observation:
- A diabetic woman presented with dyspnea, abdominal pain, and nausea.
- Autopsy revealed erosive cystitis and massive thrombo-embolic clots occluding pulmonary circulation.
Findings:
- This case presents the first reported fatal instance of septic pulmonary thromboembolism originating from erosive cystitis.
- The findings challenge existing literature by establishing a novel link between these conditions.
Implications:
- Highlights a rare but lethal complication of erosive cystitis.
- Suggests considering urinary tract infections as a potential source for SPE.
- Emphasizes the importance of thorough autopsy in identifying uncommon disease associations.
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Endocarditis II: Clinical Features of Infective Endocarditis
Urinary Tract Infection II: Pathophysiology
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Acute Pyelonephritis II: Diagnostic Studies and Management

