Related Experiment Video
Updated: Dec 23, 2025

The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire
Published on: December 23, 2014
Ultrasound-detected venous changes associated with peripheral intravenous placement in children
Dewansh Goel1, Anilawan Smitthimedhin1, Bhupender Yadav1
1Children's National Medical Center, Washington, DC.
Insights
Ultrasound revealed significant venous changes in pediatric patients with peripheral intravenous catheters (PIVs), including narrowing and thrombosis, which may explain device failure even without physical exam findings.
Area of Science:
- Pediatric Medicine
- Vascular Imaging
- Medical Devices
Background:
- Peripheral intravenous catheters (PIVs) are essential for pediatric patient care but often fail before treatment completion.
- The underlying causes of PIV failure in children are not fully understood.
- Ultrasound (US) imaging may reveal subclinical venous changes associated with PIV use.
Purpose of the Study:
- To describe and document venous changes in pediatric patients using PIVs via ultrasound imaging.
- To investigate the correlation between PIV dwell time and observed venous alterations.
Main Methods:
- A prospective study involving ultrasound scans of PIV-containing veins in pediatric patients.
- Evaluation of venous characteristics including diameter, wall thickness, blood flow, and presence of thrombus.
- Recording of patient demographics and PIV details.
Main Results:
- Ultrasound identified venous changes in 73% of accessed veins in 30 pediatric patients.
- Common findings included lumen narrowing (47%), wall thickening (33%), and thrombus formation (20%).
- Absence of blood flow around the PIV tip was observed in 40% of cases.
Conclusions:
- Ultrasound can detect significant venous changes in pediatric patients with PIVs, often not apparent on physical examination.
- These US-detectable venous alterations, such as narrowing and thrombosis, likely contribute to PIV malfunction and failure.
- Further research with larger sample sizes is warranted to fully characterize these findings and their clinical implications.
Highlights:
Ultrasound shows several venous changes in pediatric PIV-containing veins. Changes were visualized by ultrasound in the absence of physical exam findings. Venous luminal narrowing, wall thickening, and thrombosis may explain PIV failure.
Background:
Peripheral intravenous catheters (PIVs) are routinely used for venous access in hospitalized pediatric patients to administer fluids and medications and to aspirate blood. Unfortunately, PIVs do not remain functional for the entire duration of intravascular need. We hypothesized that PIV malfunction may be related to venous changes that can be visualized with ultrasound (US) imaging. The purpose of this study was to describe and document such changes in pediatric patients.
Methods:
This Institutional Review Board-approved study was performed at a tertiary pediatric medical center. Patients underwent US scans of their PIV-containing veins, documenting venous characteristics such as depth, diameter, wall thickness, blood flow, valves, branch points, and presence of thrombus. Patient demographics and PIV characteristics were also recorded.
Results:
Data from 30 patients including 12 males and 18 females with a mean age of 11 years were analyzed. Mean venous depth and diameter were 2.07 ± 0.13 and 2.02 ± 0.18 mm, respectively. Mean PIV dwell time at time of evaluation was 3.3 days. PIV-associated venous changes were seen in 73% of accessed veins and included lumen narrowing (47%), wall thickening (33%), presence of thrombus (20%), and absence of blood flow around the PIV tip (40%).
Conclusion:
PIV-associated venous changes are seen with US in the majority of pediatric patients with indwelling PIVs but are not necessarily appreciated on physical exam. These changes may help explain the high rate of pediatric PIV device failure. Given the small sample size, further investigation is needed to better characterize PIV-associated venous changes in children.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Venous Thrombosis III: Interprofessional Care
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Venous Thrombosis IV: Nursing Management

